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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: Q7Z4L1




USC-OGP 2-DE database:  Q7Z4L1


Q7Z4L1


General information about the entry
View entry in simple text format
Entry nameQ7Z4L1
Primary accession numberP63241
Secondary accession number(s) Q7Z4L1
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=Rev-binding factor; AltName: Full=eIF-4D;.
Gene nameName=EIF5A
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=6.59; Mw=17706

Cross-references
UniProtKB/Swiss-ProtP63241; IF5A1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameIF5A1_HUMAN
Primary accession numberP63241
Secondary accession number(s) A8K9A0 D3DTP2 P10159 Q16182 Q7L7L3 Q7Z4L1 Q9D0G2
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on March 15, 2017 (version 138)
Name and origin of the protein
DescriptionRecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=Rev-binding factor; AltName: Full=eIF-4D;
Gene nameName=EIF5A
Encoded onName=EIF5A
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Elongation factor; Endoplasmic reticulum; Hypusine; Membrane; mRNA transport; Nuclear pore complex; Nucleus; Protein biosynthesis; Protein transport; Reference proteome; RNA-binding; Translocation; Transport.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM23419; AAA58453.1; -; mRNA
EMBLS72024; AAD14095.1; -; Genomic_DNA
EMBLU17969; AAA86989.1; -; Genomic_DNA
EMBLAY129319; AAN17514.1; -; mRNA
EMBLAY129320; AAN17515.1; -; mRNA
EMBLAY129321; AAN17516.1; -; mRNA
EMBLAY129322; AAN17518.1; -; mRNA
EMBLAK292615; BAF85304.1; -; mRNA
EMBLCH471108; EAW90219.1; -; Genomic_DNA
EMBLCH471108; EAW90220.1; -; Genomic_DNA
EMBLCH471108; EAW90221.1; -; Genomic_DNA
EMBLCH471108; EAW90222.1; -; Genomic_DNA
EMBLBC000751; AAH00751.1; -; mRNA
EMBLBC001832; AAH01832.1; -; mRNA
EMBLBC030160; AAH30160.1; -; mRNA
EMBLBC080196; AAH80196.1; -; mRNA
EMBLBC085015; AAH85015.1; -; mRNA
EMBLBC107779; AAI07780.1; -; mRNA
CCDSCCDS11099.1; -. [P63241-1]; .
CCDSCCDS45601.1; -. [P63241-2]; .
PIRB31486; FIHUA; .
RefSeqNP_001137232.1; NM_001143760.1. [P63241-2]; .
RefSeqNP_001137233.1; NM_001143761.1. [P63241-1]; .
RefSeqNP_001137234.1; NM_001143762.1. [P63241-1]; .
RefSeqNP_001961.1; NM_001970.4. [P63241-1]; .
RefSeqXP_005256566.1; XM_005256509.2. [P63241-1]; .
UniGeneHs.104825; -; .
UniGeneHs.534314; -; .
PDB1FH4; Model; -; A=1-154
PDB3CPF; X-ray; 2.50 A; A/B=15-151
PDB5DLQ; X-ray; 3.20 A; E/F=15-154
PDBsum1FH4; -; .
PDBsum3CPF; -; .
PDBsum5DLQ; -; .
ProteinModelPortalP63241; -; .
SMRP63241; -; .
BioGrid108299; 48; .
IntActP63241; 27; .
MINTMINT-1829069; -; .
STRING9606.ENSP00000336702; -; .
TCDB1.I.1.1.3; the nuclear pore complex (npc) family; .
iPTMnetP63241; -; .
PhosphoSitePlusP63241; -; .
SwissPalmP63241; -; .
BioMutaEIF5A; -; .
DMDM54037409; -; .
DOSAC-COBS-2DPAGEP63241; -; .
OGPP63241; -; .
EPDP63241; -; .
MaxQBP63241; -; .
PaxDbP63241; -; .
PeptideAtlasP63241; -; .
PRIDEP63241; -; .
TopDownProteomicsP63241-1; -. [P63241-1]; .
TopDownProteomicsP63241-2; -. [P63241-2]; .
DNASU1984; -; .
EnsemblENST00000336452; ENSP00000336702; ENSG00000132507. [P63241-2]; .
EnsemblENST00000336458; ENSP00000336776; ENSG00000132507. [P63241-1]; .
EnsemblENST00000416016; ENSP00000396073; ENSG00000132507. [P63241-1]; .
EnsemblENST00000419711; ENSP00000390677; ENSG00000132507. [P63241-1]; .
EnsemblENST00000571955; ENSP00000458269; ENSG00000132507. [P63241-1]; .
EnsemblENST00000573542; ENSP00000459611; ENSG00000132507. [P63241-1]; .
EnsemblENST00000576930; ENSP00000459196; ENSG00000132507. [P63241-1]; .
GeneID1984; -; .
KEGGhsa:1984; -; .
UCSCuc002gfr.3; human. [P63241-1]; .
CTD1984; -; .
DisGeNET1984; -; .
GeneCardsEIF5A; -; .
HGNCHGNC:3300; EIF5A; .
HPACAB005042; -; .
HPAHPA061298; -; .
MIM600187; gene; .
neXtProtNX_P63241; -; .
OpenTargetsENSG00000132507; -; .
PharmGKBPA27726; -; .
eggNOGKOG3271; Eukaryota; .
eggNOGCOG0231; LUCA; .
GeneTreeENSGT00390000003738; -; .
HOVERGENHBG001104; -; .
InParanoidP63241; -; .
KOK03263; -; .
OMAIVEISTT; -; .
PhylomeDBP63241; -; .
TreeFamTF101534; -; .
ReactomeR-HSA-204626; Hypusine synthesis from eIF5A-lysine; .
ChiTaRSEIF5A; human; .
EvolutionaryTraceP63241; -; .
GeneWikiEIF5A; -; .
GenomeRNAi1984; -; .
PMAP-CutDBP63241; -; .
PROPR:P63241; -; .
ProteomesUP000005640; Chromosome 17; .
BgeeENSG00000132507; -; .
CleanExHS_EIF5A; -; .
ExpressionAtlasP63241; baseline and differential; .
GenevisibleP63241; HS; .
GOGO:0005642; C:annulate lamellae; IDA:UniProtKB; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0005643; C:nuclear pore; IDA:UniProtKB; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0047485; F:protein N-terminus binding; IPI:UniProtKB; .
GOGO:0043022; F:ribosome binding; IEA:InterPro; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0003746; F:translation elongation factor activity; ISS:UniProtKB; .
GOGO:0017070; F:U6 snRNA binding; IDA:UniProtKB; .
GOGO:0006915; P:apoptotic process; IDA:UniProtKB; .
GOGO:0006406; P:mRNA export from nucleus; IMP:UniProtKB; .
GOGO:0006913; P:nucleocytoplasmic transport; IMP:UniProtKB; .
GOGO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; TAS:Reactome; .
GOGO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl; .
GOGO:0008284; P:positive regulation of cell proliferation; IGI:UniProtKB; .
GOGO:0045901; P:positive regulation of translational elongation; ISS:UniProtKB; .
GOGO:0045905; P:positive regulation of translational termination; IEA:InterPro; .
GOGO:0006611; P:protein export from nucleus; IMP:UniProtKB; .
GOGO:0006452; P:translational frameshifting; IEA:InterPro; .
Gene3D2.30.30.30; -; 1; .
InterProIPR012340; NA-bd_OB-fold; .
InterProIPR014722; Rib_L2_dom2; .
InterProIPR019769; Trans_elong_IF5A_hypusine_site; .
InterProIPR001884; Transl_elong_IF5A; .
InterProIPR020189; Transl_elong_IF5A_C; .
InterProIPR008991; Translation_prot_SH3-like; .
PANTHERPTHR11673; PTHR11673; 1; .
PfamPF01287; eIF-5a; 1; .
PIRSFPIRSF003025; eIF5A; 1; .
SMARTSM01376; eIF-5a; 1; .
SUPFAMSSF50104; SSF50104; 1; .
SUPFAMSSF50249; SSF50249; 1; .
TIGRFAMsTIGR00037; eIF_5A; 1; .
PROSITEPS00302; IF5A_HYPUSINE; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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